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To dream that you are in handcuffs suggest that something or someone is holding back your success. Opportunities are shut off to you. You are experiencing a loss of power and effectiveness. Alternatively, your own fears and doubts may be holding you back.
To see others in handcuffs or to put handcuffs on others indicate that you are being overly possessive.
In particular, to dream that you or someone is in fuzzy handcuffs implies that you are ready to take a relationship to the next level.