To dream that you lose something indicates that you may really have misplaced something that you had not realized yet. It may also be a signal for you to clean out and reorganize your life. Perhaps you are overwhelmed and distracted with the hustle and bustle of day-to-day life. Alternatively, losing something often coincides with a significant life change or waking issue.
On a symbolic note, losing things in your dream suggests lost opportunities, past relationships or forgotten aspects of yourself. Your personal associations to the thing you lose will clue you into the emotional meaning and interpretation of your dream.